Dear reader: This page is part of a series of articles written for vision professionals. If that’s not you, it might not make much sense. If you’d like to learn all about eyes, vision impairment and what you can do about it, I strongly recommend you start by reading the article series I wrote for everyone, which starts here (click).
This site is in the process of being updated, with extra content designed for the layperson as well as vision professionals. I’m afraid the formatting of existing pages has been affected — sorry about that. It’s still readable, but hopefully it will all be fixed up soon, better than before.
With achromatopsia, we’re dealing with the rod response only. We’re used to thinking of the rods as only being relevant in scotopic and mesopic conditions, but they’re contributing in the lower photopic light levels as well — it’s just that their contribution is dwarfed by the cone response.
Remember that throughout these discussions I’ve only been considering the VV for mesopic levels and upwards. To really consider the full VV for rods we’d need to extend the chart quite a bit into the lower illumination levels.
Without any cones, we’d expect to see a substantial loss of the high spatial frequencies, but less impairment in mesopic conditions, and no impairment in scotopic conditions.

What this makes clear is how critically-important filters are going to be, to shift normal illumination levels down into the visual volume.